Whether we start from mid-December 2019 or mid-February, 2020, the amount of new information is increasingly rapid. With in a remarkably short time, so much is being learned about the disease that it must now be called a disease spectrum. Of course the primary end-organ affected is the ACE2 receptor bearing lungs.

But as the chart below indicates, ACE2 receptors, in varying amounts occur in almost any organ. Thus, any organ may be targeted by SARS2 for penetration, insertion and replication.

For those interested in the electron microscopic scale of analysis the following diagram of viral penetration of cellular outer membrane and pirating of reverse transcriptase activity is illustrated here. By the way, zinc interference with viral activation of reverse transcriptase is a major factor in disease suppression.

Continuing the subject of zinc, this following chart tells of similarities between SARS2 symptoms and zinc deficiency.

Ontology (taxonomy) of the corona viruses. Note the absence of influenza genera in this list. SARS2 is not the flu. Certain similarities are present, just as there are certain similarities between monkeys and men.

Here's more detail than most of you likely care for. The following diagram indicates some of the intricacies of viral machinery operating it's Henry Ford-like assembly line. Henry didn't use enzymes but SARS2 likes those friendly turncoats against the body housing them.

The above diagram and many others used here come from the excellent MedCram series by intensivist-pulmonologist Dr. Seheult.

Infectivity

What is the R0 (R naught)? No answer. Initially the U.sS. associated figure was 2.6. I have previously shown that such a figure did not represent the case of real life giant petri dish experiment occurring on the Diamond Princess. Refreshing your memories, this was a boat docked in Yokohama harbor on Jan. 31. It then cruise back to the good old U.S.A. but was quarantined at sea until Feb. 26. Of 3700 passengers and crew, only 600+ were infected by the disembarkment of Feb. 26. With R0 of 2.6, more would have been affected. Also death rate was relatively low, less than the 6 to 8 % figure often bandied about. I'll try to reference this essay.

Morbidity by the numbers:

As a percentage of the population, this number is unknown. Amongst those I consider Class B patients, the rate is largely mystery. Class B = persons with proven infection, who develop antibodies and never had a single symptom, of which there are many.

CFR (case fatality rate) is still undetermined and indeterminable until a statistically satisfactory population is sample, chosen at random, regardless of health status, contact information, genetics, etc. This knowledge deficit cannot be remedied until adequate testing occurs.

Here is an example of influenza mortality in the past 10 years to use as a comparator:

Washington State figures 2014-2020 are illustrative of regional results. These figures definitely will only roughly correspond to results from other geographic regions.

The following slides are reproduced by the excelled Peak Prosperity programs hosted by Dr. Chris Martensen, PhD Pathology.

Of which step 4 is more closely analyzed and then followed by some conclusions as of today's date. These conclusions are definitely likely to change.

Brief notes on therapy

Waiting for a vaccine is a death sentence for society. This wait fritters away the "golden hour" during which the critically ill patient may yet be saved. But awaiting the Big Pharma trillion dollar vaccines allows the prostrate patient to exsanguinate. Millicent, we have the cure! Oh, poor Millie succumbed three months ago. But don't send flowers, please.

Morphogensis of an old reliable, eminently safe drug into a hellish MONSTER. Chloroquine (CQ) and it's younger scion Plaquenil (HCQ) have been tolerated by tens of millions of people taking hundreds of millions of doses. But now, CQ and HCQ are being equated by the MSM and Mousey Fauci (sorry about the politics, folks, but that's life as we know it) equated to Zyklon B.

Yes, the Trumpites, working diligently in their underground laboratories beneath Cheyenne Mountain for at least 30 years, have now translated essentially safe CQ into a man-killer the likes of which have not been seen since the aforementioned I.G. Farben pharmaceutical grade cure-all.

The following slide comes from W.H.O. generated during the innocent pre-SARS2 era. In it, please note an absence:

How's that again?

"Despite hundreds of millions of doses administered in the treatment of malaria, there have been no reports of sudden unexplained death associated with quince, chloroquine or amodiaquine, although each drug causes QT/QTc interval prolongation. Unfortunately there are relatively few prospective studies of the electrocardiac effects of these drugs.

Oh, but certainly this drug is evil. I can smell it from the fevered denunciations (all greater than 38˚C) by the Mostly Swamp News. Awful. What are they hiding? Alligator Ed, what are you hiding? Other than my enormous appetite, I hide nothing.

Let us read along with the following scientific article discussing precisely arrhthmogenicity of hydroxychloroquine and azithromycin. The illustration is the article's conclusion. Look for MedCram videos on HC and HCQ for more information.

Look at the list of CQ side-effects as listed frequently occurring with CQ and HCQ. Frequency generally implies an incidence of between 1 to 3 percent of the population using a drug.

It seems the QT/QTc and other cardiac rhythm disturbances in the top problems.

Precious little information has come from studies. There is a duplicitous and misleading VA study showing increased death amongst treated patient compared to non-CQ treated patients. This paper amounts to scientific deception, bordering on fraud. One of the videos listed below deals with that.

But do these drugs do any good? Once again, gold-standard randomized controlled sample tests (RCTs) are missing. The following results illustrated from Brazil does not satisfy the criteria for adequate randomization but the results, nevertheless, are impressive.

Reduction of hospitalization in the treated patient was 2.8 times less than non-CQ-treated patients.

There lots of new things which I have not discussed, such as multi-organ involvement, atypical presentation. Class B patients can't be said to be atypical, since I believe future testing will indicate that less than half of confirmed cases will have been symptomatic.

In my field, knowledge, to be shared later involves neurologic manifestations of SARS2. Some of these can occur as the only symptom, e.g., anosmia.

Discussion of Diamond Princess epidemiology in relation to R0 calculation.

Lies, damned lies and coronavirus statistics.

This is not the flu.

Thorough rebuttal of CQ unfounded criticisms

Lack of supporting data for cardiac deaths due to CQ and HCQ.

More to come.