The Dose 12-13-2021

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The Dose is an open thread dedicated to the gentle discussion of of all things Covid. Please refrain from posting covid material elsewhere. Thank you.

The floor is yours

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Dawn's Meta's picture

$5/month to Trial Site News

State Vaccination Rate (2 doses) Trend (up or down)
Vermont 74.52% Historical Spike in cases; Death rate unacceptably high
Rhode Island 74.31% Historical Spike in cases; Death rate Stabilized
Maine 73.67% Historical Spike in cases; Death rate unacceptably high
Connecticut 73.13% Historical Spike in cases; Death rate Stabilized
Massachusetts 72.59% Historical Spike in cases; Death rate unacceptably high
New York 69.46% Rising Cases—a spike; Death rate stabilized
West Virginia 68.99% Surge in cases—unacceptable death rate
New Jersey 68.88% Surge in cases—death rate stabilized
Maryland 68.84% Recent surge may be waning—recent unacceptable death rate appears on the decline

*****************************************

Least Vaccinated States
State Vaccination Rate (2 doses) Trend (up or down)
Idaho 45.63% Decline in cases—unacceptable death rate
Wyoming 46.39% Decline in cases—unacceptable death rate
Alabama 46.67% Stabilized—cases and deaths way down
Mississippi 47.53% Stabilized—cases and deaths way down
Louisiana 49.35% Stabilized—cases and deaths way down
North Dakota 49.55% Cases up-still in a surge; deaths unacceptably high
Georgia 49.77% Stabilized—cases and deaths on way down
Arkansas 50.07% Cases (and deaths) appear on way back up after decline
Tennessee 50.18% Cases way down; deaths unacceptably high
Indiana 51.14% Surge in cases—death rates way down but still too many

However, breakthrough infections appear to markedly rise based on the general observation that the most vaccinated states experience greater surges now as compared to the top 10 most unvaccinated states.

ETA: Link to Trial Site News, which may be behind a paywall.
States most and least vaccinated

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A society grows great when old men plant trees in whose shade they know they shall never sit. Allegedly Greek, but more possibly fairly modern quote.

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Lookout's picture

@Dawn's Meta

Suggest many COVID deaths are vaccine deaths. If it's not been 14 days since your jab, it is counted as a unvaccinated COVID death.

Young healthy athletes are dying after vaccination.
https://rightsfreedoms.wordpress.com/2021/12/10/298-athlete-cardiac-arre...

In a sane world these vaccines would be suspended, and replaced by cheap effective early treatment, but our for-profit sickness doesn't look at what's good for people.

Pluto enlightened me about the 1918 pandemic.
https://caucus99percent.com/comment/552839#comment-552839
...and it's vax related.
https://www.unz.com/lromanoff/the-1918-rockefeller-us-army-worldwide-pan...

The more I learn the more I'm anti this vax. Not sayin' what others should or shouldn't do.

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“Until justice rolls down like water and righteousness like a mighty stream.”

CB's picture

@Lookout
See my post below.

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Pluto's Republic's picture

@CB

I'm not sure why. But I have a theory about people with dark complexions living above the 35th parallel. The "public health system" should be saving their lives by pushing Vitamin D3, instead of allowing them to die out of negligence.

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____________________

The political system is what it is because the People are who they are. — Plato
CB's picture

@Pluto's Republic
as far as I can see.

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snoopydawg's picture

@Lookout

good information to these threads. You can add your name to it because you do bring lots of information about vitamins and healthy eating and great videos. I too thank everyone who is trying to figure out what is happening.

This video is from the article on mass hysteria I posted yesterday and it’s a good listen to see why so many people are not tolerant of information that deviates from the main Fauci message. It goes with many being anxious of this whole saga and needing to find ways to be grounded.

Here’s the main gist of it.

Dr. Desmet argues that “mass formation is a specific phenomenon that emerges if certain conditions are met”:

The conditions are:

1. A lack of social connectedness;

2. A lack of meaning;

3. Free-floating anxiety (that is unconnected to any mental representation); and

4. Free-floating frustration and aggression.

(Obviously our modern society met all of these conditions prior to COVID.)

And then he argues that “a narrative is distributed via mass media that focuses anxiety and aggression on a certain object” (in this case a virus).

“When people start to participate in the strategy to deal with the object of anxiety a new kind of social bond and a new kind of meaning-making emerges.” Desmet calls it a “new kind of solidarity.”

This new narrative creates a heroic battle with the object of anxiety which leads to a “mental intoxication of connectedness” and (calming) feelings of order and control.

The more absurd the narrative the better it functions as a ritual because it shows that the participants belong to a group.

And through this process, people come to participate in, support, and identify with totalitarian systems.

I found the link to this from a comment in Alex Berensten's sub stack. It’s why I always read comments in various articles. Lots of smart people have also been trying to make sense of this.

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snoopydawg's picture

@snoopydawg

will be more acceptable to totalitarian society and we have talked a lot about global passports tied to our way of life and how the PTB can rule over us more affectively. Looky what is being planned.

Biometric Surveillance Coming Soon to an Airport Near You. Your Face Will Be Your Boarding Pass!

The biosecurity surveillance state is continuing its relentless march to record our whereabouts and every bit of data about our lives. This forthcoming “all seeing eye” will soon require your biometric data in the form of facial recognition, iris-scans, and/or fingerprints in order to travel on airplanes and other means of transportation. The COVID-19 “pandemic” was used as the guise to rush the technology through while people have been rightly focusing on grave matters such as lockdowns, vaccine mandates, societal breakdowns, and economic collapse.

To alleviate the burden of verifying COVID testing and/or vaccination requirements and combat the perfect storm of lockdowns, worker shortages, and flight cancellations, airlines are turning to biometrics as a way to automate processes and provide “better” customer service. This chain of events “caused by COVID” is facilitating the rapid changeover to a surveillance system that will eventually lead to a full-fledged digital ID (beginning with vaccine passports) tracking everything you do and everywhere you go.

To say there is not enough attention being paid to this issue is a huge understatement. Once these technologies are firmly entrenched they will be nearly impossible to root out. However, as is common custom the global oligarchs are revealing their technocratic, totalitarian plans through one of their primary propaganda outlets, the New York Times.

As a way to begin preparing the population for this monumental change, the Times article states:

If it’s been a year or more since you traveled, particularly internationally, you may notice something different at airports in the United States: More steps — from checking a bag to clearing customs — are being automated using biometrics.

Biometrics are unique individual traits, such as fingerprints, that can be used to automate and verify identity. They promise both more security and efficiency in moving travelers through an airport where, at steps from check-in to boarding, passengers are normally required to show government-issued photo identification.

In the travel hiatus caused by the pandemic, many airports, airlines, tech companies and government agencies like the Transportation Security Administration and United States Customs and Border Protection continued to invest in biometric advancements. The need for social distancing and contactless interactions only added to the urgency.

People willingly accepted the TSA after 9/11 and even though they haven’t caught one terrorist trying to board a plane people are still subjected to their groping daily. Kids, grannies and veterans are stripped of their 4th amendment right and treated as if they are guilty of some unknown crime. "It’s better to be safe than sorry" or "I have nothing to hide so why should I care?" No wonder congress keeps taking more of our rights. People really don’t seem to care much about them.

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snoopydawg's picture

Once again it’s only the lowly wait staff that has to wear masks. How many times have we seen this throughout these long years?

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Pluto's Republic's picture

@snoopydawg

One can go without a mask by using a nasal spray made from Iota-carrageenan, which successfully protects against SARS-CoV-2 infection. it has gone through thorough clinical trials. My guess is that's what the unmasked elite are using. Of course, to protect others in case one is infected, one should wear a mask anyway.

The CDC could tell Americans about this highly effective way to prevent Covid-19 infections. It's sold over the counter and does not require a prescription.

https://c19ic.com

We have the worst public health institutions. They should be torn down and remade by sane people who can remember what their purpose is.

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____________________

The political system is what it is because the People are who they are. — Plato
ggersh's picture

https://www.theautomaticearth.com/2021/12/debt-rattle-december-13-2021/

But in New Zealand along with the other "5 Eyes" countries we inform them with propaganda.

“Pfizer Jab Is Only 22.5% Effective Against Omicron”: South Africa study.
So obviously the UK wants 1 million jabs per day. And Fauci wants more.

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I never knew that the term "Never Again" only pertained to
those born Jewish

"Antisemite used to be someone who didn't like Jews
now it's someone who Jews don't like"

Heard from Margaret Kimberley

CB's picture

Florida Surgeon General Promotes Nutraceuticals for COVID
December 13, 2021

Story at-a-glance

  • Dr. Joseph Ladapo was appointed Florida surgeon general and secretary of the Florida Department of Health by Gov. Ron DeSantis September 21, 2021
  • Ladapo has now issued a statewide public service announcement in support of commonsense COVID prevention strategies such as optimizing your vitamin D, staying active, eating nutrient-dense foods and boosting your immune system with supplements such as vitamin C, quercetin and zinc
  • Florida Health even highlights emerging treatments such as fluvoxamine and inhaled budesonide. Importantly, Florida Health now states that “Physicians should use their clinical judgment when recommending treatment options for patients’ individualized health care needs. This may include emerging treatment options with appropriate patient informed consent, including off-label use or as part of a clinical trial”
  • Despite publishing a scientific review on vitamin D for COVID in the peer-reviewed journal Nutrients, and the paper being the second most downloaded article this year, I’ve been vilified and targeted by the U.S. Food and Drug Administration and the Federal Trade Commission for reporting its benefits
  • The evidence for vitamin D against COVID-19 satisfies Hill’s criteria for causality in a biological system, and dozens of studies have demonstrated vitamin D helps reduce all risks associated with COVID

As a ray of hope in what appears to be an utterly broken medical system, Florida’s new surgeon general, Dr. Joseph Ladapo, has issued a statewide public service announcement in support of commonsense COVID prevention strategies such as optimizing your vitamin D, staying active, eating nutrient-dense foods and boosting your immune system with supplements.

The HealthierYouFL.org website1 now urges Floridians to “Talk to your health care provider about how certain supplements or foods containing vitamins and minerals might help boost your immune system, such as zinc, vitamin D, vitamin C and quercetin.” These are all well-known supplements that have been shown to have a positive impact on your COVID-19 risk.
...

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Lookout's picture

@CB

Off with their heads!!!

Wonder how the media is covering that. I hope it is just the first of the dominoes of state officials promoting simple prevention strategies.

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“Until justice rolls down like water and righteousness like a mighty stream.”

CB's picture

@Lookout
and shutdowns August 4, 2021.

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Pluto's Republic's picture

...are vulnerable to the Omicron variant infection.

(Reuters) - Two-dose COVID-19 vaccine regimens do not induce enough neutralizing antibodies against the Omicron coronavirus variant, British scientists found, indicating that increased infections in those previously infected or vaccinated may be likely.

Researchers from the University of Oxford published results on Monday from a study yet to be peer-reviewed, where they analysed blood samples from participants who were given doses from AstraZeneca-Oxford or Pfizer-BioNTech in a large study looking into mixing of vaccines.

The results come a day after British Prime Minister Boris Johnson warned that two shots will not be enough to contain Omicron, following findings from the UK health agency last week that boosters significantly restore protection against the variant.

.
So, even if you haven't been vaccinated, just get a fresh booster jab and you're likely good to go.

On the other hand:

The Oxford study said that there was no evidence yet that the lower level of infection-fighting antibodies against Omicron could lead to higher risk of severe disease, hospitalisation or death in those who have got two doses of approved vaccines.

.
Why would anybody even think that in the first place? It's been settled that the fully vaccinated are overwhelmingly protected against serious illness or hospitalization in the majority of cases.

"These data are important but are only one part of the picture. They only look at neutralising antibodies after the second dose, but do not tell us about cellular immunity, and this will also be tested," said Matthew Snape, Oxford professor and co-author of the paper.

.
Cellular immunity? Since when did anyone achieve cellular immunity as some sort of superpower? Humans still rely on the immune system to fight the virus.
.
Reuters told the truth, then they still tried to gaslight their Readers.

This is why we can't have nice news.

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____________________

The political system is what it is because the People are who they are. — Plato
CB's picture

@Pluto's Republic
The antigens to the virus they test for are soon gone. The vaccine manufacturers only test for the antigen and gaslights us into thinking we have not achieved natural immunity and need another shot.

Cellular immunity

Cellular immunity is a protective immune process that involves the activation of phagocytes, antigen-sensitized cytotoxic T cells and the release of cytokines and chemokines in response to antigen. Cellular immunity is most effective against cells infected with viruses, intracellular bacteria, fungi and protozoans, and cancerous cells. It also mediates transplant rejection.

Difference Between T Cells And B Cells

B cells and T cells are the white blood cells of the immune system that are responsible for adaptive immune response in an organism. Both the cells are made in the bone marrow. B cells mature in the bone marrow while the T cells travel to the thymus and mature there.

These cells are structurally similar and are involved in adaptive immune response in an organism.
...
What are B cells?

These cells mature in the bone marrow and produce antibodies in response to the antigens. B cells are involved in humoral response. As soon as B cells come across the antigens, they produce plasma cells and memory B cells.

What are T cells?

T cells originate in the bone marow and mature in the thymus. These can be further divided into T helper cells and T cytotoxic cells. They are responsible for removing the pathogens from the body. As soon as the foreign antigen enters the cells, T cells trigger the B cells to develop plasma cells and activates T killer cells that kill the cells affected by the invaders.

Similarities between B cells and T cells

  1. Both B and T cells originate in the bone marrow.
  2. These cells are involved in adaptive immunity.
  3. They are a type of lymphocytes.
  4. The cells are nucleated and motile.
  5. Both protect the body’s immune system and help fighting infections.
  6. Both the cells are non-phagocytic and are a part of lymphatic system.

...

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I do not want to spoil it for those who haven't read it. I will say, this is a plandemic to the extent that WHO, FDA, CDC, the CIA, Pharma, and GAVI, have a planned protocol that is rehearsed, planned, reinacted, down to the initial reports of the first person to become ill, the masks, lockdowns, censorship, use of the military, how to present the reports of cases and deaths, the methodology of non-placebo group testing, the emphasis upon instilling fear and isolation, the move to authoritarianism, is the script that has been in place since the first world war.
Not to leave out, any repurposed, inexpensive drug protocols is ALWAYS prohibited, in favor of a designated treatment, if any, and a vaccination that has not been rigorously tested.
In all pandemic scenarios, Pharma has complete immunity

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"We'll know our disinformation program is complete when everything the American public believes is false." ---- William Casey, CIA Director, 1981

zed2's picture

More pers on promising molecules in the fight against covid. These are from the peer reviewed scientific literature.

Stilbene-based natural compounds as promising drug candidates against COVID-19
https://pubmed.ncbi.nlm.nih.gov/32345140/

The pandemic coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents a great threat to public health. Currently, no potent medicine is available to treat COVID-19. Quest for new drugs especially from natural plant sources is an area of immense potential. The current study aimed to repurpose stilbenoid analogs, reported for some other biological activities, against SARS-CoV-2 spike protein and human ACE2 receptor complex for their affinity and stability using molecular dynamics simulation and binding free energy analysis based on molecular docking. Four compounds in total were probed for their binding affinity using molecular docking. All of the compounds showed good affinity (> -7 kcal/mol). However, fifty nanoseconds molecular dynamic simulation in aqueous solution revealed highly stable bound conformation of resveratrol to the viral protein: ACE2 receptor complex. Net free energy of binding using MM-PBSA also affirmed the stability of the resveratrol-protein complex. Based on the results, we report that stilbene based compounds in general and resveratrol, in particular, can be promising anti-COVID-19 drug candidates acting through disruption of the spike protein. Our findings in this study are promising and call for further in vitro and in vivo testing of stiblenoids, especially resveratrol against the COVID-19. [Formula: see text] Communicated by Ramaswamy H. SarmaHighlightsStilbenoid analogs could be potential disruptors of SARS-CoV-2 spike protein and human ACE2 receptor complex.In particular, resveratrol revealed highly stable conformation to the viral protein: ACE2 receptor complex.The strong interaction of resveratrol is affirmed by molecular dynamic simulation studies and better net free energies.

Keywords: COVID-19; MM-PBSA; Stilbenoids; molecular docking; molecular dynamic simulations.

----------------------------------

Targeting autophagy with natural products to prevent SARS-CoV-2 infection
PMID: 34664025 PMCID: PMC8516241 DOI: 10.1016/j.jtcme.2021.10.003

Abstract
Autophagy is a catabolic process that maintains internal homeostasis and energy balance through the lysosomal degradation of redundant or damaged cellular components. During virus infection, autophagy is triggered both in parenchymal and in immune cells with different finalistic objectives: in parenchymal cells, the goal is to destroy the virion particle while in macrophages and dendritic cells the goal is to expose virion-derived fragments for priming the lymphocytes and initiate the immune response. However, some viruses have developed a strategy to subvert the autophagy machinery to escape the destructive destiny and instead exploit it for virion assembly and exocytosis. Coronaviruses (like SARS-CoV-2) possess such ability. The autophagy process requires a set of proteins that constitute the core machinery and is controlled by several signaling pathways. Here, we report on natural products capable of interfering with SARS-CoV-2 cellular infection and replication through their action on autophagy. The present study provides support to the use of such natural products as adjuvant therapeutics for the management of COVID-19 pandemic to prevent the virus infection and replication, and so mitigating the progression of the disease.

Keywords: COVID-19; Coronavirus; Pandemic; Phytotherapy; Resveratrol; Virophagy.

© 2021 Center for Food and Biomolecules, National Taiwan University. Production and hosting by Elsevier Taiwan LLC.

Recent progress in the development of potential drugs against SARS-CoV-2.
Chen J, Ali F, Khan I, Zhu YZ.

Curr Res Pharmacol Drug Discov. 2021;2:100057. doi: 10.1016/j.crphar.2021.100057. Epub 2021 Sep 14.
PMID: 34870155 Free PMC article. Review.

Molecular Mechanisms of Possible Action of Phenolic Compounds in COVID-19 Protection and Prevention.
Gligorijevic N, Radomirovic M, Nedic O, Stojadinovic M, Khulal U, Stanic-Vucinic D, Cirkovic Velickovic T.
Int J Mol Sci. 2021 Nov 17;22(22):12385. doi: 10.3390/ijms222212385.
PMID: 34830267

Coronavirus interactions with the cellular autophagy machinery.
Miller K, McGrath ME, Hu Z, Ariannejad S, Weston S, Frieman M, Jackson WT.
Autophagy. 2020 Dec;16(12):2131-2139. doi: 10.1080/15548627.2020.1817280. Epub 2020 Sep 23.
PMID: 32964796 Free PMC article. Review.
Autophagy/virophagy: a "disposal strategy" to combat COVID-19.
Mijaljica D, Klionsky DJ.
Autophagy. 2020 Dec;16(12):2271-2272. doi: 10.1080/15548627.2020.1782022. Epub 2020 Jun 24.
PMID: 32578486 Free PMC article.
The Unfolded Protein Response and Autophagy on the Crossroads of Coronaviruses Infections.
Prestes EB, Bruno JCP, Travassos LH, Carneiro LAM.
Front Cell Infect Microbiol. 2021 Apr 28;11:668034. doi: 10.3389/fcimb.2021.668034. eCollection 2021.
PMID: 33996638 Free PMC article. Review.
Digesting the crisis: autophagy and coronaviruses.
Carmona-Gutierrez D, Bauer MA, Zimmermann A, Kainz K, Hofer SJ, Kroemer G, Madeo F.
Microb Cell. 2020 May 4;7(5):119-128. doi: 10.15698/mic2020.05.715.
PMID: 32391393 Free PMC article.
Therapeutic Potential of Exploiting Autophagy Cascade Against Coronavirus Infection.
Maity S, Saha A.
Front Microbiol. 2021 May 14;12:675419. doi: 10.3389/fmicb.2021.675419. eCollection 2021.
PMID: 34054782 Free PMC article. Review.

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snoopydawg's picture

@zed2

Currently, no potent medicine is available to treat COVID-19. Quest

that have been approved by Fauci. There are quite a few drugs that have been shown to treat it.

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CB's picture

@zed2
at this late stage of the game, that studies for a prophylaxis for COVID are at the least in the in vivo stage for efficacy and safety. In silico or in vitro studies puts them so far into the future that they are effectively meaningless for us. What we want are repurposed drugs which have shown a good safety profile and that can be put to the test in a year or less. Another factor is any new drugs, if found to be effective, would be patented and sold for thousands of dollars - hundreds of times their production costs.

We already have off-patent drugs like ivermectin and hydroxychloroquine which have proven to be effective, safe AND inexpensive. Unfortunately TPTB are preventing their wide distribution, even to the point of making them illegal, especially in the western countries where there has been regulatory capture by the drug companies.

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snoopydawg's picture

@CB

Pfizer is saying that their new drug is 95% effective against the Rona. Alrighty then that means that there are at least 3 treatments available for treating it so now vaccines shouldn’t get EAU and there should be no way that they can be mandated. Let’s see Fauci explain getting around that rule.

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CB's picture

@snoopydawg
BTW, the new drug is under a EUA so it can't be mandated AND you can't sue if things go sideways. The others are NOT approved by the FDA for use in COVID-19. It will require a double blind placebo trials using a bazillion subjects by the drug companies or the NIH before Fauci would approve them.

there should be no way that they can be mandated. Let’s see Fauci explain getting around that rule.

The vaccine can be mandated because it's an APPROVED vaccine - Comirnaty. But at the VERY SAME TIME it is also under an EUA.

Voldemort Fauci gets to have his cake and and keep it too. "There is no good and evil, there is only power and those too weak to seek it!" - Lord Voldemort.

See the following for the Magical Manipulation:

Q&A for Comirnaty (COVID-19 Vaccine mRNA)
...
How is Comirnaty (COVID-19 Vaccine, mRNA) related to the Pfizer-BioNTech COVID-19 Vaccine?

The FDA-approved Comirnaty (COVID-19 Vaccine, mRNA) and the two EUA authorized formulations of Pfizer-BioNTech COVID-19 Vaccine for ages 12 years and older, when prepared according to their respective instructions for use, can be used interchangeably without presenting any safety or effectiveness concerns. Therefore, providers can use doses distributed under EUA to administer the vaccination series as if the doses were the licensed vaccine. For purposes of administration, doses distributed under the EUA are interchangeable with the licensed doses. The Vaccine Information Fact Sheet for Recipients and Caregivers provides additional information about both the approved and authorized vaccines.

Is Comirnaty interchangeable with other COVID-19 vaccines?

The FDA-approved Comirnaty (COVID-19 Vaccine, mRNA) and the two EUA authorized formulations of Pfizer-BioNTech COVID-19 Vaccine for ages 12 years and older, when prepared according to their respective instructions for use, can be used interchangeably without presenting any safety or effectiveness concerns. The products are legally distinct with certain differences that do not impact safety or effectiveness.
...

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