Sickle cell trait makes Covid-19 infections more serious
Black people are more likely to die of Covid-19.
Although economic disparities are a major factor in developing severe infections, another factor is the high prevalence of sickle cell trait among people with ancestry from areas of Africa where malaria is endemic.
People with sickle cell disease are known to be at higher risk of severe illness from covid-19. The virus is known to increase blood clotting in seriously affected individuals whether they have a blood disease or not.
People with sickle cell anemia got the gene that causes the anemia from both parents. People with sickle cell trait got the anemia gene from one parent and a normal gene from the other parent. They are likely to have more serious problems with covid-19 than people with the normal gene from both parents.
According to the CDC on May 16, 2020:
SCD affects approximately 100,000 Americans.
SCD occurs among about 1 out of every 365 Black or African-American births.
SCD occurs among about 1 out of every 16,300 Hispanic-American births.
About 1 in 13 Black or African-American babies is born with sickle cell trait (SCT).
This is why I was so concerned about the situation in the favelas in Brazil. Many people there are not only living in overcrowded conditions, but also are descended from former African and indigenous slaves. There is a very high rate of sickle cell trait in many parts of Africa, although the relative youth of the people in many African countries will somewhat mitigate the problems.
Edited for spelling typos